Follow these instructions to reach the casino: Mystic Lake Casino is roughly 30 miles from downtown St. You will arrive at Mystic Lake Casino on your left.ĭirections to Mystic Lake Casino from Downtown St.Take US-169 S to Mystic Lake Dr NW in Prior Lake. The casino is approximately 25 miles from downtown Minneapolis. Your destination, Mystic Lake Casino, will be on your left.ĭirections to Mystic Lake Casino from Downtown Minneapolis.Turn left onto County Rd 83/Marschall Rd.Take the County Rd 83 exit toward Canterbury Rd/Shakopee.Merge onto MN-5 W via the ramp to I-494.Start by heading southwest on Glumack Dr toward Airport Ser Rd.